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E3 ligase Ligand-Linker Conjugates 48

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128832
    Nutlin-C1-amido-PEG4-C2-N3

    MDM2 Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 48

    		 E3 Ligase Ligand-Linker Conjugates Cancer
    Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology. Nutlin-C1-amido-PEG4-C2-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Nutlin-C1-amido-PEG4-C2-N3
  • HY-162201
    E3 Ligase Ligand-linker Conjugate 48

    		Ligands for E3 Ligase Cancer
    E3 Ligase Ligand-linker Conjugate 48 is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.
    <em>E3</em> <em>Ligase</em> <em>Ligand-linker</em> <em>Conjugate 48</em>

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